In the women's singles, fourth seed Osaka survived a ding-dong battle against Kostyuk to emerge victorious 6-3, 6-7 (4), 6-2 after two hours and 33 minutes.
"Ensuring a safe return to international table tennis has been our utmost priority ever since the pandemic broke out. I am delighted that, with the fantastic support and hard work carried out by everyone at the ITTF over several months, we have managed to get events back up and running before the end of 2020," said the ITTF President Thomas Weikert.
Behind the top three, Norris took fourth ahead of an out of sorts Bottas, who looked off the pace all day and appeared to suffer with handling and overheating problems.
Kenin, who won her first Grand Slam title at this year's Australian Open, did not face a break point in her match against 17-year-old Fernandez before nailing her convincing win.
Chasing his 18th Grand Slam singles title, world number one Djokovic was in total control against his 28th-seeded opponent, winning 6-3, 6-3, 6-1 in one hour and 42 minutes to progress to the last 16 in the men's singles.
Djokovic's unexpected exit ends both his 26-match winning streak this year and his attempt to win his 18th Grand Slam title, with the drama also sending Carreno Busta into the men's quarterfinals.
However, the hectic last 11 games saw Atletico find form and as rivals such as Real Sociedad and Getafe lost ground, in the end the top four was secured with relative ease.
In the men's shot put, Ryan Crouser of the U.S. won with a throw of 22.70m, followed by Poland's Michal Haratyk and Leonardo Fabbri from Italy.
"All the players have to stay in the two hotels booked by organizers without exception."
Yates was dropped on the final climb of the 153km from Pau to Laruns, which was the second day that the race took place in the Pyrenees.
The Austrian will now challenge 2014 champion Marin Cilic of Croatia in the third round. Thiem has a 2-0 lead in their head-to-head series.